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For example, Orlistat, which is a medication that inhibits pancreatic lipase, reduces dietary fat by approximately 30% Research suggests that those on the medication are more likely to lose weight and regain less weight than control groups after treatment (Aronne, 2001; Rivas-Vazquez, Rice, & Kalman, 2003) Side effects include gastrointestinal upset, fecal urgency, oily or soft stool, diarrhea, and flatus with discharge (Rivas-Vazquez et al, 2003) Sibutramine is another approved medication to treat obesity that inhibits the reuptake of several neurotransmitters such as serotonin and norepinephrine Like Orlistat, those who take Sibutramine tend to be more likely to lose weight and regain less weight than others following treatment (Aronne, 2001; Rivas-Vazquez et al, 2003) Side effects include increases in heart rate and blood pressure Research continues to find other biological interventions for obesity.

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For example, ciliary neurotrophic factor (CNTF) is a promising protein that activates the intracellular signaling pathways in the hypothalamus that regulates both body weight and food consumption (Rivas-Vazquez et al, 2003) Thus, it activates the satiety center in the brain to signal that the person is no longer hungry Research suggests that it is effective in helping control weight The FDA has given fast track status to CNTF (likely to be sold as the medication, Axokine) These medications, when used in combination with other biopsychosocial interventions, may be useful to the millions of Americans who are obese However, too often the public gets overly invested and excited about a promising easy way to control weight Numerous medications, fad diets, and gadgets have been sold to the public only to be found to be ineffective or even dangerous.

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23 Graber, ER and Rudich Y Atmospheric HULIS: how humic-like are they A comprehensive and critical review Atmospheric Chemistry and Physics 2006; 6: 729 753 24 Cachier, H Carbonaceous combustion aerosols In: RM Harrison and R van Grieken, eds Atmospheric Particles John Wiley, New York: 1998 25 Wentzel, M, Gorzawski, H, Naumann, KH, Saathoff, H and Weinbruch, S Transmission electron microscopical and aerosol dynamical characterization of soot aerosols Journal of Aerosol Science 2003; 34: 1347 1370 26 Martins, JV, Artaxo, P, Liousse, C, Reid, JS, Hobbs, PV and Kaufman, YJ Effects of black carbon content, particle size, and mixing on light absorption by aerosols from biomass burning in Brazil Journal of Geophysical Research 1998; 103(D24): 32041 32050 27 Akhter, MS, Chughtai, AR and Smith, DM.

The structure of hexane soot, I: extraction studies Applied Spectroscopy 1985; 39: 154 167 28 Hamilton, RS and Mans eld, TA Airborne particulate elemental carbon its sources, transport and contribution to dark smoke and soiling Atmospheric Environment 1991; 25: 715 723 29 Cass, GR, Boone, PM and Macias, ES Emissions and air quality relationships for atmospheric carbon particles in Los Angeles In: GT Wolff and RL Klimisch, eds Particulate Carbon: Atmospheric Life Cycle Plenum Press, New York: 1982; pp 207 243 30 Grosjean, D In situ organic aerosol formation during a smog episode: estimated production and chemical functionality Atmospheric Environment 1992; 26: 953 963 31 Turpin, BJ and Huntzicker, JJ Identi cation of secondary organic aerosol episodes and quantitation of primary and secondary organic aerosol concentrations during SCAQS Atmospheric Environment 1995; 29: 3527 3544 32 Odum, JR.

A good example is the excitement regarding the obesity medication, phentermine resin-fenfluramine or phen-fen which was very popular in the early and mid-1990s The FDA banned the drug in 1997 when it became clear that patients on the medication were at higher risk for heart valve problems You must proceed cautiously with weight loss products such as medications, allowing research to adequately determine the effectiveness and safety of the product..

, Hoffmann, T, Bowman, F, Collins, D, Flagan, RC and Seinfeld, JH Gas/particle partitioning and secondary organic aerosol yield Environmental Science and Technology 1996; 30: 2580 2585 33 Lazaridis, M Gas-particle partitioning of organic compounds in the atmosphere Journal of Aerosol Science 1999; 30(9): 1165 1170 34 Limbeck, A, Kraxner, Y and Puxbaum, H Gas to particle distribution of low molecular weight dicarboxylic acids at two different sites in central Europe (Austria) Journal of Aerosol Science 2005; 36(8): 991 1005 35 Grif n, RJ, Cocker, DR, III, Flagan, RC and Seinfeld, JH Organic aerosol formation from oxidation of biogenic hydrocarbons Journal of Geophysical Research 1999; 104: 3555 3567 36 Seigneur, C, Pai, P, Louis, J-F, Hopke, P and Grosjean, D Review of air quality models for particulate matter Prepared for the American Petroleum Institute.

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