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J Neurol Neurosurg Psychiatry 65:810, 1998 BUTTERWORTH RF, GIGUIERE JF, MICHAUD J, et al: Ammonia: Key factor in the pathogenesis of hepatic encephalopathy Neurochem Pathol 6:1, 1987 CAO X-Y, JIAN GX-M, DOU Z-H, et al: Timing of vulnerability of the brain to iodine de ciency in endemic cretinism N Engl J Med 331:1739, 1994 CAVANAGH JB: Liver bypass and the glia, in Plum F (ed): Brain dysfunction in metabolic disorders Res Publ Assoc Res Nerv Ment Dis 53:13, 1974 CHOI DW, ROTHMAN SM: The role of glutamate neurotoxicity in hypoxicischemic neuronal death Annu Rev Neurosci 13:171, 1990 CHOI IS: Delayed neurologic sequelae in carbon monoxide intoxication Arch Neurol 40:433, 1983 CHONG JY, ROWLAND LP, UTIGER RD: Hashimoto encephalopathy: Syndrome or myth Arch Neurol 60:164, 2003 COOKE WT, SMITH WT: Neurologic disorders associated with adult coeliac disease Brain 89:683, 1966 CREMER GM, GOLDSTINE NP, PARIS J: Myxedema and ataxia.

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Integrating Metabolic Pathways ATP Glucose Storage Molecules Metabolic States and Signals Insulin Glucagon Epinephrine Secondary Signals Generalities of Metabolism Phosphorylation Glycogen Metabolic Movements of Glycogen Fat Metabolic Movements of Fat Protein Metabolic Movements of Protein Tissue Cooperation Liver Muscle Adipose Brain Connection of Storage Pools Feeding Fasting Starvation Excitement Interorgan Cycles Cori Cycle Alanine Cycle Ketone Bodies

Neurology 19:37, 1969 CROSS AH, GOLUMBEK PT: Neurologic manifestations of celiac disease Neurology 60:1566, 2003 DAHLQUIST NR, PERRAULT J, CALLAWAY CW: D-Lactic acidosis and encephalopathy after jejunoileostomy: Response to overfeeding and to fasting in humans Mayo Clin Proc 59:141, 1984 DELONG GR, STANBURY JB, FIERRO-BENITEZ R: Neurological signs in congenital iodine-de ciency disorder (endemic cretinism) Dev Med Child Neurol 27:317, 1985 DIMAURO S, TONIN P, SERVIDEI S: Metabolic myopathies, in Rowland LP, DiMauro S (eds): Handbook of Clinical Neurology Vol 18 New York, Elsevier, 1992, pp 479 526 DOOLING EC, RICHARDSON EP JR: Delayed encephalopathy after strangling Arch Neurol 33:196, 1976 EAYRS JT: In uence of the thyroid on the central nervous system Br Med Bull 16:122, 1960 FARRELL RJ, KELLY CP: Celiac sprue N Engl J Med 346:180, 2002 FERRACCI F, MORETT OG, CANDEAGO RM, et al: Antithyroid antibodies in the CSF.

COGAN DG: Myasthenia gravis: A review of the disease and a description of lid twitch as a characteristic sign Arch Ophthalmol 74:217, 1965 COHEN MS, YOUNGER D: Aspects of the natural history of myasthenia gravis: Crisis and death Ann NY Acad Sci 377:670, 1981 COMPSTON DAS, VINCENT A, NEWSOM-DAVIS A, BATCHELOR JR: Clinical, pathological, HLA antigen, and immunological evidence for disease heterogeneity in myasthenia gravis Brain 103:579, 1980 CROXEN R, HATTAN C, SHELLAY C, et al: Recessive inheritance and variable penetrance of slow-channel congenital myasthenic syndromes Neurology 59:162, 2002 DAU PC, DENYS EH: Plasmapheresis and immunosuppressive therapy in the Eaton-Lambert syndrome Ann Neurol 11:570, 1982 DE FEO LG, SCHOTTLENDER J, MARTELLI NA, et al: Use of intravenous pulsed cyclophosphamide in severe generalized myasthenia gravis Muscle Nerve 26:31, 2002 DRACHMAN DB: How to recognize an antibody-mediated autoimmune disease: Criteria, in Waksman BH (ed): Immunologic Mechanisms in Neurologic and Psychiatric Disease.

Value 1,000 pF /.001 F 1,500 pF /.0015 F 2,000 pF /.002 F 2,200 pF /.0022 F 4,700 pF /.0047 F 5,000 pF /.005 F 5,600 pF /.0056 F 6,800 pF /.0068 F .01 .015 .02 .022 .033

Their role in the pathogenesis of Hashimoto s encephalopathy Neurology 60:712, 2003..

Res Publ Assoc Res Nerv Ment Dis 68: 183, 1990 DRACHMAN DB: Myasthenia gravis N Engl J Med 330:1797, 1994 DRACHMAN DB: Myasthenic antibodies cross-link acetylcholine receptors to accelerate degradation N Engl J Med 298:136, 186, 1978 DRACHMAN DB, JONES RJ, BRODSKY RA: Treatment of refractory myasthenia: rebooting with high dose cyclophosphamide Ann Neurol 53: 29, 2003 EATON LM, LAMBERT EH: Electromyography and electric stimulation of nerves and diseases of motor unit: Observations on myasthenic syndrome associated with malignant tumors JAMA 163:1117, 1957 ELMQUIST D, LAMBERT EH: Detailed analysis of neuromuscular transmission in a patient with the myasthenic syndrome, sometimes associated with bronchial carcinoma Mayo Clin Proc 43:689, 1968 ENGEL AG: Congenital myasthenic syndromes, in Engel AG (ed): Myasthenia Gravis and Myasthenic Disorders New York, Oxford University Press, 1999, pp 251 297 ENGEL AG (ed): Myasthenia Gravis and Myasthenic Disorders New York, Oxford University Press, 1999.

TABLE 4-1.

(continued )

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