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The Pocket PCs to be distributed to the field force come with software that enables the technicians to work with the device without having to con nect to the back-office system. The synchronization functionality will enable the exchange of updates whenever appropriate. Later, we will see that this will be done on a frequent basis. At the start of the project, the aim was to reduce administration costs and increase service revenue through better utilization of the technicians and streamlined data capture. As we will see later, there were a number of addi tional parameters that were also improved, including customer satisfaction and logistics.

The simplest way to make a Flash projector file is to use the Publish feature of Flash. In three short steps, you can have a stand-alone Flash movie presentation. 1. Select File Publish Settings from the main menu. 2. When the Publish Settings dialog opens, select the Formats tab and then check the projector formats. Publish both Windows and Macintosh projectors using this method. Figure 42-2 shows the Publish Settings dialog with the appropriate formats selected.

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his book describes SketchUp Process Modeling, a methodology for working with SketchUp. This approach provides a step-by-step road map that will show you how to use the tools and functions to construct expressive models of exterior spaces and architecture. The process addresses three main areas of instruction: drafting, modeling order, and organization. Mastering these skills will allow you to create models that are highly detailed and articulate, easy to work with, optimized for computer performance, and organized. Figs. 1-1 through 1-3 and Figs. 1-8 through 1-13 are examples of site plans and architectural projects created using SketchUp Process Modeling. It is important to note that the book contents and tutorials were designed to work with SketchUp 7. It is strongly suggested that readers download the free version of SketchUp 7 from SketchUp s web site (www.sketchup.com).

7

Indirect DNA damage is mediated by free radicals. When particulate or photon radiation interacts with water (H2 O) an ion pair is formed (H2 O+ , e ). The electron will combine with H2 O to form H2 O . The H2 O+ and H2 O are called ion radicals (not to be confused with free radicals). Ion radicals are very unstable and rapidly dissociate: H2 O+ becomes H+ and OH , and H2 O becomes H and OH . OH and H are free radicals. A free radical is an atom or molecule that has no electrical charge but is highly reactive because it has an odd number of electrons with an unpaired electron in its outer shell. Free radicals tend to quickly recombine to form stable electron con gurations. However, in high enough concentrations in the cell, they can create organic free radicals (R ) and H2 O (hydrogen peroxide), 2 a toxic molecule. OH + RH become R + H2 O and two OH become H2 O2 . Organic free radicals in DNA lead to breakage of the strands and cross-linking. OH , since it oxidizes (removes electrons), is more damaging than H , which is a reducing agent (gives up its electrons).

the small intestine walls. The absorbed nutrients are delivered to the circulatory system and liver (Figure 8.11). Undigested food residues, highly colonized by microorganisms, enter the large intestine whose bands of exterior muscles and inner-surface goblet cells dehydrate and absorb nutrients from the gut contents until they are released as feces. It is in the large intestine (cecum, rising colon, transverse colon, sigmoid colon, plus descending colon) where a symbiosis (mutualism) analogous to those listed in Table 8.1 (entries 1 and 2, for herbivorous animals) develops for humans (B ckhed et al., 2005). Box 8.3 provides a summary of the recently recognized bene ts contributed to humans by their intestinal micro ora. Also summarized in Box 8.3 are the results of two recent nonculture-based inquiries attempting to characterize the composition and metabolic function of the intestinal micro ora. In terms of molecular sequencing effort (see Sections 6.7 and 6.9), the two studies were massive. In the rst study, a 16S rRNA approach documented more than 13,000 taxonomic sequences from 21 intestinal or fecal samples from three healthy individuals. One striking result from the study was the fact that 1524 archaeal sequences belonged to a single group (Methanobrevibacter smithii). This apparently limited archaeal diversity could possibly be a result of polymerase chain reaction (PCR) bias (see Section 6.7) in the methodology. Alternatively, this result may reveal

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