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(d) Only faculty in the department with deptid=33 teach more than three courses (e) Every student must be enrolled in the course called Math101 (f) The room in which the earliest scheduled class (ie, the class with the smallest meets at value) meets should not be the same as the room in which the latest scheduled class meets (g) Two classes cannot meet in the same room at the same time (h) The department with the most faculty members must have fewer than twice the number of faculty members in the department with the fewest faculty members (i) No department can have more than 10 faculty members (j) A student cannot add more than two courses at a time (ie, in a single update) (k) The number of CS majors must be more than the number of Math majors (l) The number of distinct courses in which CS majors are enrolled is greater than the number of distinct courses in which Math majors are enrolled (m) The total enrollment in courses taught by faculty in the department with deptid=33 is greater than the number of Math majors (n) There must be at least one CS major if there are any students whatsoever (o) Faculty members from di erent departments cannot teach in the same room Exercise 59 Discuss the strengths and weaknesses of the trigger mechanism Contrast triggers with other integrity constraints supported by SQL Exercise 510 Consider the following relational schema An employee can work in more than one department; the pct time eld of the Works relation shows the percentage of time that a given employee works in a given department Emp(eid: integer, ename: string, age: integer, salary: real) Works(eid: integer, did: integer, pct time: integer) Dept(did: integer, budget: real, managerid: integer) Write SQL-92 integrity constraints (domain, key, foreign key, or CHECK constraints; or assertions) or SQL:1999 triggers to ensure each of the following requirements, considered independently 1 Employees must make a minimum salary of $1,000 2 Every manager must be also be an employee 3 The total percentage of all appointments for an employee must be under 100% 4 A manager must always have a higher salary than any employee that he or she manages 5 Whenever an employee is given a raise, the manager s salary must be increased to be at least as much 6 Whenever an employee is given a raise, the manager s salary must be increased to be at least as much Further, whenever an employee is given a raise, the department s budget must be increased to be greater than the sum of salaries of all employees in the department.

nisms of action are poorly understood Insulin growth factor-1 (IGF-1) expression is thought to play an important role in sebum production by stimulating SG lipogenesis49 IGF-1 increases expression of a transcription factor called sterol response element-binding protein-1 (SREBP-1) SREBP-1 regulates numerous genes involved in lipid biosynthesis and its expression stimulates lipogenesis in sebocytes50 Several recently discovered receptors such as the liver X receptors (LXRs) and the peroxisome proliferatoractivated receptors (PPARs) have been shown to influence lipid metabolism and increase sebum production by such receptor agonists51,52 As research technologies improve, more insight into the processes that govern sebum secretion will likely be gleaned

Step 13: Create a Complexity Value Agenda (and Execute!)

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Once you have built a business case for each complexity target, you can compile a complete list of projects It is likely that you will have more value opportunities than resources Therefore you want to prioritize to accelerate the value creation The principal prioritization is by value-atstake However, a secondary prioritization is the consideration of the nature of the project: Is it highly customer-focused, and hence more urgent What is the risk profile for the project (and moreover, what risks exist that cannot be managed away through select investments) Once you ve made the selection, compile the list of projects and their expected contribution to value creation, and identify the priority sequence Summarize the results in a bar chart like that shown in Figure 81 (another example is shown later)

tant role in the link between stress and sebum production55 The SG also possesses receptors for substance P, which is a neuromediator released in response to stress56 In vitro, substance P stimulates sebaceous secretion57 It is postulated that substance P plays a role in acne as a response to stress

Obviously space does not permit us to walk you through a complete case study of a business, but we will give you a flavor for how these tools are used by returning to the EGI company we ve been following Part of the picture we did not address in earlier chapters was the Strategic Position analysis, depicted in Figure 811

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Although many products claim to inhibit sebum production, very few, if any, have been conclusively proven to work Most oil control products on the market contain talc and other oilabsorbing components that mask or absorb oil rather than function as sebum production inhibitors Antiandrogens such as ketoconazole and spironolactone have shown some effects76,77 Progesterone has demonstrated a shortterm effect (2 3 months) when applied topically in women However, it has not reduced sebum excretion rates in men78 Corticosteroids, erythromycinzinc complex, elubiol (dichlorophenyl imidazoldioxolan), and recently an extract from saw palmetto, sesame seeds, and argan oil have all been used for this purpose79 82 Notably, topical retinoids have not been shown to decrease sebum secretion83

Figure 811: EGI Strategic Position Chart (One year ago and today)

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