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When EGI created its CVSM, one family they identified consisted of only two products for their small contractor customer base Now EGI wants to investigate the impact of simply stopping production of that family (in our terms, they d be simplifying their product portfolio) Here are the relevant data for the entire manufacturing process, fabrication through shipping, before changes are made Total Lead Time is 6 weeks (240 hrs) Total VA = 192 minutes PCE = VA/TLT = 192 min / 240 hr * 60 min/hr = 13% WIP = $24M or 4800 equivalent finished generators (average cost of $500, sales price of $626,GPM of 20%) Exit rate = 4800/240 = 20 Generators per hour output Aggregate demand = 20 pc / hr Steps in process = 25 Parts in process = 6 Cumulative Setup Times = 3 hr Processing Time = 0008 hr / pc (each unit takes more than 0008 hrs, but this is scaled by the number of parallel assembly stations) If the two small contractor products were dropped but everything else remained the same (again calculated from the full Complexity Equation)

with eicosapentaenoic acid in the treatment of atopic dermatitis Br J Dermatol 1987;117:463 Callaway J, Schwab U, Harvima I, et al Efficacy of dietary hempseed oil in patients with atopic dermatitis J Dermatolog Treat 2005;16:87 Morse NL, Clough PM A meta-analysis of randomized, placebo-controlled clinical trials of Efamol evening primrose oil in atopic eczema Where do we go from here in light of more recent discoveries Curr Pharm Biotechnol 2006;7:503 Kanehara S, Ohtani T, Uede K, et al Undershirts coated with borage oil alleviate the symptoms of atopic dermatitis in children Eur J Dermatol 2007;17:448 Krajcovicova-Kudlackova M, Simoncic R, Bederova A, et al Lipid and antioxidant blood levels in vegetarians Nahrung 1996;40:17 Melchert HU, Limsathayourat N, Mihajlovic H, et al Fatty acid patterns in triglycerides, diglycerides, free fatty acids, cholesteryl esters and phosphatidylcholine in serum from vegetarians and non-vegetarians Atherosclerosis 1987;65:159 Li D, Ball M, Bartlett M, et al Lipoprotein(a), essential fatty acid status and lipoprotein lipids in female Australian vegetarians Clin Sci (Lond) 1999;97:175 Suzuki R, Shimizu T, Kudo T, et al Effects of n-3 polyunsaturated fatty acids on dermatitis in NC/Nga mice Prostaglandins Leukot Essent Fatty Acids 2002;66:435 Davis BC, Kris-Etherton PM Achieving optimal essential fatty acid status in vegetarians: current knowledge and practical implications Am J Clin Nutr 2003;78:640S Rosell MS, Lloyd-Wright Z, Appleby PN, et al Long-chain n-3 polyunsaturated fatty acids in plasma in British meat-eating, vegetarian, and vegan men Am J Clin Nutr 2005;82:327 Kim HH, Cho S, Lee S, et al Photoprotective and anti-skin-aging effects of eicosapentaenoic acid in human skin in vivo J Lipid Res 2006; 47:921 Krajcovicova-Kudlackova M, Simoncic R, Babinska K, et al Lipid parameters in blood of vegetarians Cor Vasa 1993;35: 224 Tomobe YI, Morizawa K, Tsuchida M, et al Dietary docosahexaenoic acid suppresses inflammation and immunoresponses in contact hypersensitivity reaction in mice Lipids 2000;35:61 Simopoulos AP Omega-3 fatty acids in health and disease and in growth and development Am J Clin Nutr 1991;54: 438 Mayser P, Mrowietz U, Arengerger P, et al Omega-3 fatty acid-based lipid infusion in patients with chronic plague psoriasis: results of a double-blind, randomized, placebo-controlled, multicenter trial J Am Acad Dermatol 1998;39: 539 Pronczuk A, Kipervarg Y, Hayes KC Vegetarians have higher plasma alphatocopherol relative to cholesterol than do nonvegetarians J Am Coll Nutr 1992;11:50 Boelsma E, Hendriks HF, Roza L Nutritional skin care: health effects of.

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A common use of triggers is to maintain database consistency, and in such cases, we should always consider whether using an integrity constraint (eg, a foreign key constraint) will achieve the same goals The meaning of a constraint is not de ned operationally, unlike the e ect of a trigger This property makes a constraint easier to understand, and also gives the DBMS more opportunities to optimize execution A constraint also prevents the data from being made inconsistent by any kind of statement, whereas a trigger is activated by a speci c kind of statement (eg, an insert or delete statement) Again, this restriction makes a constraint easier to understand On the other hand, triggers allow us to maintain database integrity in more exible ways, as the following examples illustrate Suppose that we have a table called Orders with elds itemid, quantity, customerid, and unitprice When a customer places an order, the rst three eld values are lled in by the user (in this example, a sales clerk) The fourth eld s value can be obtained from a table called Items, but it is important to include it in the Orders table to have a complete record of the order, in case the price of the item is subsequently changed We can de ne a trigger to look up this value and include it in the fourth eld of a newly inserted record In addition to reducing the number of elds that the clerk has to type in, this trigger eliminates the possibility of an entry error leading to an inconsistent price in the Orders table

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