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It is relatively simple to construct a DAC by taking advantage of the summing ampli er illustrated in 12 Consider the circuit shown in Figure 1524, where each bit in the word to be converted is represented by means of a 5-V source and a switch When the switch is closed, the bit takes a value of 1 (5 V); when the switch is open, the bit has value 0 Thus, the output of the DAC is proportional to the word bn 1 bn 2 b1 b0 You will recall that a property of the summing ampli er is that the sum of the currents at the inverting node is zero, yielding the relationship va = RF bi 5 Ri i = 0, 1, , n 1 (1524)

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lost.To their credit, the workers were quick to retract their conclusions. Currently, there are intriguing results suggesting that divorce, aggression, and dyslexia are under genetic in uence. For example, in a recent study, investigators measured a heritability of 0.52 for divorce. This doesn t mean that divorce genes exist, but rather that genes for certain personality traits might predispose a person to divorce. We should make it clear that genetic control does not mean that the environment does not play a role in these traits, just that there are genes that are in uential also, sometimes very signi cantly. In retrospect, it should not be surprising that genes in uence much of our behavior. There are numerous animal studies con rming genetic control of behaviors, indicating that the same would be found in people. As long as the research is done in a competent fashion and the results are not politicized, human behavior genetics should not only be a reasonable area of study, but an exciting one as we learn more about ourselves.

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where Ri is the resistor associated with each bit and bi is the decimal value of the ith bit (ie, b0 = 20 , b1 = 21 , and so on) It is easy to verify that if we select Ri = R0 2i (1525)

Figure 1524 n-bit digital-to-analog converter (DAC)

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STUDY OBJECTIVE 1: To understand the patterns of inheritance of phenotypic traits controlled by many loci 531 535 Some genetically controlled phenotypes do not fall into discrete categories. This type of variation is referred to as quantitative, continuous, or metrical variation. The genetic control of this variation is referred to as polygenic control. If the number of controlling loci is small, and offspring fall into recognizable classes, it is possible to analyze the genetic control of the phenotypes with standard methods. Polygenes controlling DDT resistance are located on all chromosomes in Drosophila. STUDY OBJECTIVE 2: To investigate the way that geneticists and statisticians describe and analyze normal distributions of phenotypes 535 542 When phenotypes fall into a continuous distribution, the methods of genetic analysis change. We must describe a distribution using means, variances, and standard deviations. Then we must describe the relationship between two variables using variances and correlation coef cients.

we can obtain weighted gains for each bit so that va = RF n 1 (2 bn 1 + + 21 b1 + 20 b0 ) Vin R0 (1526)

The resistance ratio governs most of the performance characteristics of the hydrostatic bearing For design purposes, the practical values of x can be considered to be in the range of 05 80 x = x =

and so that the analog output voltage is proportional to the decimal representation of the binary word As an illustration, consider the case of a four-bit word; a reasonable choice for R0 might be R0 = 10 k , yielding a resistor network consisting of 10-, 5-, 25-, and 125-k resistors, as shown in Figure 1525 The largest decimal value of a four-bit word is 24 1 = 15, and so it is reasonable to divide this range into steps of 1 volt (ie, v = 1 V) Thus, the full-scale value of va is 15 V: 0 va 15 V and we select RF according to the following expression: RF = v R0 1 104 = =2k Vin 5

1. Several cases mentioned in the text reported and then retracted the discovery of human genes controlling speci c traits. Barring fraud, what might cause a scientist to retract a study of this type

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2. Monozygotic twins share identical genes. Under what conditions could they show discordance of traits

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